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Artesunate prevents rats from the clozapine-induced hepatic steatosis and elevation in plasma triglycerides

Clozapine is an atypical antipsychotic with therapeutic efficacy in treatment-resistant schizophrenia patients and low incidence of extrapyramidal side effects. However, the use of clozapine has been limited by its adverse effects on metabolism. Artesunate is a semisynthetic derivative of artemisini...

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Detalles Bibliográficos
Autores principales: Li, Yanmei, Su, Ruibing, Xu, Shuqin, Huang, Qingjun, Xu, Haiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627760/
https://www.ncbi.nlm.nih.gov/pubmed/29026311
http://dx.doi.org/10.2147/NDT.S145069