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A genetic variant in the catechol-O-methyl transferase (COMT) gene is related to age-dependent differences in the therapeutic effect of calcium-channel blockers
Hypertension is the leading risk factor for cardiovascular disease and one of the major health concerns worldwide. Genetic factors impact both the risk for hypertension and the therapeutic effect of antihypertensive drugs. Sex- and age-specific variances in the prevalence of hypertension are partly...
Autores principales: | Xu, Jiayue, Boström, Adrian E., Saeed, Mohamed, Dubey, Raghvendra K., Waeber, Gérard, Vollenweider, Peter, Marques-Vidal, Pedro, Mwinyi, Jessica, Schiöth, Helgi B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627798/ https://www.ncbi.nlm.nih.gov/pubmed/28746172 http://dx.doi.org/10.1097/MD.0000000000007029 |
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