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VASA mRNA (DDX4) detection is more specific than immunohistochemistry using poly- or monoclonal antibodies for germ cells in the male urogenital tract
VASA, also known as DDX4, is reported to be specifically expressed in cells belonging to the germ cell lineage, both in males and females. Therefore, it could be an informative protein biomarker to be applied on semen to differentiate between obstructive and nonobstructive azoospermia (OA and NOA, r...
Autores principales: | Boellaard, Willem P.A., Stoop, Hans, Gillis, Ad J.M., Oosterhuis, J. Wolter., Looijenga, Leendert H.J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627816/ https://www.ncbi.nlm.nih.gov/pubmed/28746190 http://dx.doi.org/10.1097/MD.0000000000007489 |
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