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MAPK/p38 regulation of cytoskeleton rearrangement accelerates induction of macrophage activation by TLR4, but not TLR3

Toll-like receptor 3 (TLR3) and TLR4 utilize adaptor proteins to activate mitogen-activated protein kinase (MAPK), resulting in the acute but transient inflammatory response aimed at the clearance of pathogens. In the present study, it was demonstrated that macrophage activation by lipopolysaccharid...

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Detalles Bibliográficos
Autores principales: Bian, Hongjun, Li, Feifei, Wang, Wenwen, Zhao, Qi, Gao, Shanshan, Ma, Jincai, Li, Xiao, Ren, Wanhua, Qin, Chengyong, Qi, Jianni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627867/
https://www.ncbi.nlm.nih.gov/pubmed/28949380
http://dx.doi.org/10.3892/ijmm.2017.3143