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DCs facilitate B cell responses against microbial DNA via DC-SIGN

Microbial DNA is highly immunostimulatory and is sensed by endosomal pattern recognition receptors after release from internalized microbes. It is unclear how extracellular DNA released from dead microbes is delivered to endosomal PRRs to induce immune responses. Here we have investigated the abilit...

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Detalles Bibliográficos
Autores principales:	Sprokholt, Joris K., Heineke, Marieke H., Kaptein, Tanja M., van Hamme, John L., Geijtenbeek, Teunis B. H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627929/ https://www.ncbi.nlm.nih.gov/pubmed/28976999 http://dx.doi.org/10.1371/journal.pone.0185580

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