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Altering neuronal excitability to preserve network connectivity in a computational model of Alzheimer's disease

Neuronal hyperactivity and hyperexcitability of the cerebral cortex and hippocampal region is an increasingly observed phenomenon in preclinical Alzheimer’s disease (AD). In later stages, oscillatory slowing and loss of functional connectivity are ubiquitous. Recent evidence suggests that neuronal d...

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Detalles Bibliográficos
Autores principales:	de Haan, Willem, van Straaten, Elisabeth C. W., Gouw, Alida A., Stam, Cornelis J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627940/ https://www.ncbi.nlm.nih.gov/pubmed/28938009 http://dx.doi.org/10.1371/journal.pcbi.1005707

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