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The Kaposi's sarcoma-associated herpesvirus (KSHV) non-structural membrane protein K15 is required for viral lytic replication and may represent a therapeutic target

Kaposi’s sarcoma-associated herpesvirus (KSHV) is the infectious cause of the highly vascularized tumor Kaposi’s sarcoma (KS), which is characterized by proliferating spindle cells of endothelial origin, extensive neo-angiogenesis and inflammatory infiltrates. The KSHV K15 protein contributes to the...

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Detalles Bibliográficos
Autores principales: Abere, Bizunesh, Mamo, Tamrat M., Hartmann, Silke, Samarina, Naira, Hage, Elias, Rückert, Jessica, Hotop, Sven-Kevin, Büsche, Guntram, Schulz, Thomas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627962/
https://www.ncbi.nlm.nih.gov/pubmed/28938025
http://dx.doi.org/10.1371/journal.ppat.1006639