Recombinant vaccines of a CD4(+) T-cell epitope promote efficient control of Paracoccidioides brasiliensis burden by restraining primary organ infection

Paracoccidioidomycosis (PCM) is an infectious disease endemic to South America, caused by the thermally dimorphic fungi Paracoccidioides. Currently, there is no effective human vaccine that can be used in prophylactic or therapeutic regimes. We tested the hypothesis that the immunogenicity of the im...

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Detalles Bibliográficos
Autores principales: Holanda, Rodrigo Assunção, Muñoz, Julián Esteban, Dias, Lucas Santos, Silva, Leandro Buffoni Roque, Santos, Julliana Ribeiro Alves, Pagliari, Sthefany, Vieira, Érica Leandro Marciano, Paixão, Tatiane Alves, Taborda, Carlos Pelleschi, Santos, Daniel Assis, Bruña-Romero, Oscar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627964/
https://www.ncbi.nlm.nih.gov/pubmed/28938005
http://dx.doi.org/10.1371/journal.pntd.0005927

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