Cell cycle stage-specific transcriptional activation of cyclins mediated by HAT2-dependent H4K10 acetylation of promoters in Leishmania donovani

Chromatin modifications affect several processes. In investigating the Leishmania donovani histone acetyltransferase HAT2, using in vitro biochemical assays and HAT2-heterozygous genomic knockout we found the constitutively nuclear HAT2 acetylated histone H4K10 in vitro and in vivo. HAT2 was essenti...

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Detalles Bibliográficos
Autores principales: Chandra, Udita, Yadav, Aarti, Kumar, Devanand, Saha, Swati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627965/
https://www.ncbi.nlm.nih.gov/pubmed/28938001
http://dx.doi.org/10.1371/journal.ppat.1006615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627965/
https://www.ncbi.nlm.nih.gov/pubmed/28938001
http://dx.doi.org/10.1371/journal.ppat.1006615

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