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Vitamin D and osteoporosis in chronic kidney disease
Osteoporotic fractures are common in patients with chronic kidney disease (CKD). Morbidity and mortality are higher in CKD patients with a fracture than in the general population. The assessment of bone mineral density for fracture prediction may be useful at all CKD stages. It should be considered...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628182/ https://www.ncbi.nlm.nih.gov/pubmed/28940158 http://dx.doi.org/10.1007/s40620-017-0430-x |
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author | Lips, Paul Goldsmith, David de Jongh, Renate |
author_facet | Lips, Paul Goldsmith, David de Jongh, Renate |
author_sort | Lips, Paul |
collection | PubMed |
description | Osteoporotic fractures are common in patients with chronic kidney disease (CKD). Morbidity and mortality are higher in CKD patients with a fracture than in the general population. The assessment of bone mineral density for fracture prediction may be useful at all CKD stages. It should be considered when this influences treatment decisions. Vitamin D deficiency is common in patients with CKD, particularly in patients with proteinuria, due to loss of 25-hydroxyvitamin D and its binding protein. Vitamin D supplementation should be prescribed early in the course of renal disease. For treatment and prevention of vitamin D deficiency in CKD patients cholecalciferol 800 IU/day or the equivalent per month is recommended just as in the general population. |
format | Online Article Text |
id | pubmed-5628182 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-56281822017-10-17 Vitamin D and osteoporosis in chronic kidney disease Lips, Paul Goldsmith, David de Jongh, Renate J Nephrol Review Osteoporotic fractures are common in patients with chronic kidney disease (CKD). Morbidity and mortality are higher in CKD patients with a fracture than in the general population. The assessment of bone mineral density for fracture prediction may be useful at all CKD stages. It should be considered when this influences treatment decisions. Vitamin D deficiency is common in patients with CKD, particularly in patients with proteinuria, due to loss of 25-hydroxyvitamin D and its binding protein. Vitamin D supplementation should be prescribed early in the course of renal disease. For treatment and prevention of vitamin D deficiency in CKD patients cholecalciferol 800 IU/day or the equivalent per month is recommended just as in the general population. Springer International Publishing 2017-09-23 2017 /pmc/articles/PMC5628182/ /pubmed/28940158 http://dx.doi.org/10.1007/s40620-017-0430-x Text en © The Author(s) 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Review Lips, Paul Goldsmith, David de Jongh, Renate Vitamin D and osteoporosis in chronic kidney disease |
title | Vitamin D and osteoporosis in chronic kidney disease |
title_full | Vitamin D and osteoporosis in chronic kidney disease |
title_fullStr | Vitamin D and osteoporosis in chronic kidney disease |
title_full_unstemmed | Vitamin D and osteoporosis in chronic kidney disease |
title_short | Vitamin D and osteoporosis in chronic kidney disease |
title_sort | vitamin d and osteoporosis in chronic kidney disease |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628182/ https://www.ncbi.nlm.nih.gov/pubmed/28940158 http://dx.doi.org/10.1007/s40620-017-0430-x |
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