A rare case of CD1a‐negative Langerhans cell histiocytosis of the central nervous system in a child

Langerhans cell histiocytosis is a dendritic cell disorder with a wide spectrum of severity and presentations. Histopathology typically demonstrates a proliferation of Langerhans cells and a lymphohistiocytic inflammatory infiltrate with eosinophils. The diagnosis is supported by immunohistochemistr...

Descripción completa

Detalles Bibliográficos
Autores principales: Powell, Priscilla, Vitug, Gaile, Castro‐Silva, Fernando, Ray, Anish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628212/
https://www.ncbi.nlm.nih.gov/pubmed/29026568
http://dx.doi.org/10.1002/ccr3.1136
_version_ 1783268836706877440
author Powell, Priscilla
Vitug, Gaile
Castro‐Silva, Fernando
Ray, Anish
author_facet Powell, Priscilla
Vitug, Gaile
Castro‐Silva, Fernando
Ray, Anish
author_sort Powell, Priscilla
collection PubMed
description Langerhans cell histiocytosis is a dendritic cell disorder with a wide spectrum of severity and presentations. Histopathology typically demonstrates a proliferation of Langerhans cells and a lymphohistiocytic inflammatory infiltrate with eosinophils. The diagnosis is supported by immunohistochemistry with the cell markers S100, CD1a, CD68, and Langerin [Blood, 126, 2015, 26 and N Engl J Med, 331, 1994, 154].
format Online
Article
Text
id pubmed-5628212
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-56282122017-10-12 A rare case of CD1a‐negative Langerhans cell histiocytosis of the central nervous system in a child Powell, Priscilla Vitug, Gaile Castro‐Silva, Fernando Ray, Anish Clin Case Rep Case Reports Langerhans cell histiocytosis is a dendritic cell disorder with a wide spectrum of severity and presentations. Histopathology typically demonstrates a proliferation of Langerhans cells and a lymphohistiocytic inflammatory infiltrate with eosinophils. The diagnosis is supported by immunohistochemistry with the cell markers S100, CD1a, CD68, and Langerin [Blood, 126, 2015, 26 and N Engl J Med, 331, 1994, 154]. John Wiley and Sons Inc. 2017-09-01 /pmc/articles/PMC5628212/ /pubmed/29026568 http://dx.doi.org/10.1002/ccr3.1136 Text en © 2017 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Powell, Priscilla
Vitug, Gaile
Castro‐Silva, Fernando
Ray, Anish
A rare case of CD1a‐negative Langerhans cell histiocytosis of the central nervous system in a child
title A rare case of CD1a‐negative Langerhans cell histiocytosis of the central nervous system in a child
title_full A rare case of CD1a‐negative Langerhans cell histiocytosis of the central nervous system in a child
title_fullStr A rare case of CD1a‐negative Langerhans cell histiocytosis of the central nervous system in a child
title_full_unstemmed A rare case of CD1a‐negative Langerhans cell histiocytosis of the central nervous system in a child
title_short A rare case of CD1a‐negative Langerhans cell histiocytosis of the central nervous system in a child
title_sort rare case of cd1a‐negative langerhans cell histiocytosis of the central nervous system in a child
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628212/
https://www.ncbi.nlm.nih.gov/pubmed/29026568
http://dx.doi.org/10.1002/ccr3.1136
work_keys_str_mv AT powellpriscilla ararecaseofcd1anegativelangerhanscellhistiocytosisofthecentralnervoussysteminachild
AT vituggaile ararecaseofcd1anegativelangerhanscellhistiocytosisofthecentralnervoussysteminachild
AT castrosilvafernando ararecaseofcd1anegativelangerhanscellhistiocytosisofthecentralnervoussysteminachild
AT rayanish ararecaseofcd1anegativelangerhanscellhistiocytosisofthecentralnervoussysteminachild
AT powellpriscilla rarecaseofcd1anegativelangerhanscellhistiocytosisofthecentralnervoussysteminachild
AT vituggaile rarecaseofcd1anegativelangerhanscellhistiocytosisofthecentralnervoussysteminachild
AT castrosilvafernando rarecaseofcd1anegativelangerhanscellhistiocytosisofthecentralnervoussysteminachild
AT rayanish rarecaseofcd1anegativelangerhanscellhistiocytosisofthecentralnervoussysteminachild

Ejemplares similares