Clinical implications of cytogenetic heterogeneity in multiple myeloma patients with TP53 deletion

TP53 deletion (ΔTP53) in myeloma is known to be a high-risk finding associated with poorer prognosis. The prognostic impact of underlying cytogenetic heterogeneity in patients with myeloma associated with ΔTP53 is unknown. We studied 90 patients with myeloma associated with ΔTP53 identified by inter...

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Detalles Bibliográficos
Autores principales: Hao, Suyang, Lin, Pei, Medeiros, L Jeffrey, Fang, Lianghua, Carballo-Zarate, Adrian A, Konoplev, Sergej N, Sargent, Rachel L, Weber, Donna M, Thomas, Sheeba K, Manasanch, Elisabet E, Orlowski, Robert Z, Lu, Xinyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628266/
https://www.ncbi.nlm.nih.gov/pubmed/28664940
http://dx.doi.org/10.1038/modpathol.2017.63

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