TGF-β1 suppresses CCL3/4 expression through the ERK signaling pathway and inhibits intervertebral disc degeneration and inflammation-related pain in a rat model

The objective of this study was to investigate the regulatory effects of TGF-β1 on CCL3/4 expression and inflammation-related pain during intervertebral disc degeneration (IVDD). TGF-β1 and CCL3/4 expression patterns in different degenerative human nucleus pulposus (NP) tissues were measured by qPCR...

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Detalles Bibliográficos
Autores principales: Zhang, Jian, Li, Zemin, Chen, Fan, Liu, Hui, Wang, Hua, Li, Xiang, Liu, Xianguo, Wang, Jianru, Zheng, Zhaomin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628275/
https://www.ncbi.nlm.nih.gov/pubmed/28935976
http://dx.doi.org/10.1038/emm.2017.136

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