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Precision spherical nucleic acids for delivery of anticancer drugs

We report a spherical nucleic acid (SNA) system for the delivery of BKM120, an anticancer drug for treatment of chronic lymphocytic leukemia (CLL). While promising for cancer treatment, this drug crosses the blood–brain barrier causing significant side-effects in patients. The DNA nanoparticle encap...

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Detalles Bibliográficos
Autores principales:	Bousmail, Danny, Amrein, Lilian, Fakhoury, Johans J., Fakih, Hassan H., Hsu, John C. C., Panasci, Lawrence, Sleiman, Hanadi F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2017
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628336/ https://www.ncbi.nlm.nih.gov/pubmed/28989655 http://dx.doi.org/10.1039/c7sc01619k

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