Elucidation of the relative and absolute stereochemistry of the kalimantacin/batumin antibiotics

Kalimantacin A and batumin exhibit potent and selective antibiotic activity against Staphylococcus species including MRSA. Both compounds are formed via a hybrid polyketide synthase/non-ribosomal peptide synthetase (PKS-NRPS) biosynthetic pathway and from comparison of the gene clusters it is appare...

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Detalles Bibliográficos
Autores principales: Thistlethwaite, Iain R. G., Bull, Freya M., Cui, Chengsen, Walker, Paul D., Gao, Shu-Shan, Wang, Luoyi, Song, Zhongshu, Masschelein, Joleen, Lavigne, Rob, Crump, Matthew P., Race, Paul R., Simpson, Thomas J., Willis, Christine L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628338/
https://www.ncbi.nlm.nih.gov/pubmed/28989652
http://dx.doi.org/10.1039/c7sc01670k

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