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Transmembrane TNF-α Density, but not Soluble TNF-α Level, is Associated with Primary Response to Infliximab in Inflammatory Bowel Disease
OBJECTIVES: Anti-tumor necrosis factor (TNF)-α agents like Infliximab (IFX) are effective in the treatment of inflammatory bowel diseases (IBDs) and are widely used. However, a considerable number of patients do not respond or lose response to this therapy. Preliminary evidence suggests that transme...
Autores principales: | Amini Kadijani, Azade, Asadzadeh Aghdaei, Hamid, Sorrentino, Dario, Mirzaei, Alireza, Shahrokh, Shabnam, Balaii, Hedieh, Nguyen, Vu Q, Mays, Jessica L, Reza Zali, Mohammad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628358/ https://www.ncbi.nlm.nih.gov/pubmed/28914262 http://dx.doi.org/10.1038/ctg.2017.44 |
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