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Status of Serum Vitamin D and Calcium Levels in Women of Reproductive Age in National Capital Territory of India

CONTEXT: In India, Vitamin D deficiency is a major public health problem, associated with lack of sunlight exposure in spite of abundant sunshine usually accompanied by reduced dietary intake. In women of reproductive age, Vitamin D deficiency in pregnancy has been associated with an increased risk...

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Detalles Bibliográficos
Autores principales: Sofi, Nighat Yaseen, Jain, Monika, Kapil, Umesh, Seenu, Vuthaluru, Ramakrishnan, Lakshmy, Yadav, Chander Prakash, Pandey, Ravindra Mohan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628545/
https://www.ncbi.nlm.nih.gov/pubmed/28989883
http://dx.doi.org/10.4103/ijem.IJEM_134_17
Descripción
Sumario:CONTEXT: In India, Vitamin D deficiency is a major public health problem, associated with lack of sunlight exposure in spite of abundant sunshine usually accompanied by reduced dietary intake. In women of reproductive age, Vitamin D deficiency in pregnancy has been associated with an increased risk of gestational diabetes mellitus, preeclampsia, maternal and perinatal morbidity and mortality. AIMS: The aim of the present cross-sectional study was to evaluate the levels of serum Vitamin D 25(OH) D and calcium in women of reproductive age from India. SETTINGS AND DESIGN: A cross-sectional study was carried on a total of 224 healthy nonpregnant and nonlactating women in the reproductive age group of 20–49 years. MATERIALS AND METHODS: Demographic, socioeconomic class, and biochemical parameters for the estimation of serum 25(OH)D and calcium levels in women of reproductive age were studied. STATISTICAL ANALYSIS: Statistical Package for Social Sciences version 20.0 was utilized for conducting the statistical analysis of the data. RESULTS: Vitamin D deficiency (<20 ng/ml) was present in 88% of women. Women from middle socioeconomic class had the lowest mean serum 25(OH) D levels (9.6 ± 6 ng/ml) as compared to women from upper middle (11.4 ± 8 ng/ml), lower (11.2 ± 8 ng/ml), and upper (10 ± 8.6 ng/ml) socioeconomic class. Serum calcium levels were found in the normal range of 8.5–10.5 mg/dl for all the study subjects. CONCLUSIONS: There is a high prevalence of hypovitaminosis D among women of reproductive age. These women may possibly have a higher risk of development of osteoporosis and pregnancy-related complications in future life.