Micellar catalysis-enabled sustainable ppm Au-catalyzed reactions in water at room temperature

Several ppm level gold-catalyzed reactions enabled by the ligand HandaPhos can be performed at room temperature in aqueous nanoreactors composed of the surfactant Nok. Variously substituted allenes undergo cycloisomerization leading to heterocyclic products in good yields. Likewise, cyclodehydration...

Descripción completa

Detalles Bibliográficos
Autores principales: Klumphu, Piyatida, Desfeux, Camille, Zhang, Yitao, Handa, Sachin, Gallou, Fabrice, Lipshutz, Bruce H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628599/
https://www.ncbi.nlm.nih.gov/pubmed/28989668
http://dx.doi.org/10.1039/c7sc02405c
_version_ 1783268916841152512
author Klumphu, Piyatida
Desfeux, Camille
Zhang, Yitao
Handa, Sachin
Gallou, Fabrice
Lipshutz, Bruce H.
author_facet Klumphu, Piyatida
Desfeux, Camille
Zhang, Yitao
Handa, Sachin
Gallou, Fabrice
Lipshutz, Bruce H.
author_sort Klumphu, Piyatida
collection PubMed
description Several ppm level gold-catalyzed reactions enabled by the ligand HandaPhos can be performed at room temperature in aqueous nanoreactors composed of the surfactant Nok. Variously substituted allenes undergo cycloisomerization leading to heterocyclic products in good yields. Likewise, cyclodehydration is also illustrated under similar conditions, as is an intermolecular variant, hydration of terminal alkynes. Recycling of the catalyst and reaction medium is also illustrated. A low E factor associated with limited solvent use and therefore, waste generation, documents the greenness of this process.
format Online
Article
Text
id pubmed-5628599
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Royal Society of Chemistry
record_format MEDLINE/PubMed
spelling pubmed-56285992017-10-06 Micellar catalysis-enabled sustainable ppm Au-catalyzed reactions in water at room temperature Klumphu, Piyatida Desfeux, Camille Zhang, Yitao Handa, Sachin Gallou, Fabrice Lipshutz, Bruce H. Chem Sci Chemistry Several ppm level gold-catalyzed reactions enabled by the ligand HandaPhos can be performed at room temperature in aqueous nanoreactors composed of the surfactant Nok. Variously substituted allenes undergo cycloisomerization leading to heterocyclic products in good yields. Likewise, cyclodehydration is also illustrated under similar conditions, as is an intermolecular variant, hydration of terminal alkynes. Recycling of the catalyst and reaction medium is also illustrated. A low E factor associated with limited solvent use and therefore, waste generation, documents the greenness of this process. Royal Society of Chemistry 2017-09-01 2017-07-20 /pmc/articles/PMC5628599/ /pubmed/28989668 http://dx.doi.org/10.1039/c7sc02405c Text en This journal is © The Royal Society of Chemistry 2017 http://creativecommons.org/licenses/by/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution 3.0 Unported License (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Chemistry
Klumphu, Piyatida
Desfeux, Camille
Zhang, Yitao
Handa, Sachin
Gallou, Fabrice
Lipshutz, Bruce H.
Micellar catalysis-enabled sustainable ppm Au-catalyzed reactions in water at room temperature
title Micellar catalysis-enabled sustainable ppm Au-catalyzed reactions in water at room temperature
title_full Micellar catalysis-enabled sustainable ppm Au-catalyzed reactions in water at room temperature
title_fullStr Micellar catalysis-enabled sustainable ppm Au-catalyzed reactions in water at room temperature
title_full_unstemmed Micellar catalysis-enabled sustainable ppm Au-catalyzed reactions in water at room temperature
title_short Micellar catalysis-enabled sustainable ppm Au-catalyzed reactions in water at room temperature
title_sort micellar catalysis-enabled sustainable ppm au-catalyzed reactions in water at room temperature
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628599/
https://www.ncbi.nlm.nih.gov/pubmed/28989668
http://dx.doi.org/10.1039/c7sc02405c
work_keys_str_mv AT klumphupiyatida micellarcatalysisenabledsustainableppmaucatalyzedreactionsinwateratroomtemperature
AT desfeuxcamille micellarcatalysisenabledsustainableppmaucatalyzedreactionsinwateratroomtemperature
AT zhangyitao micellarcatalysisenabledsustainableppmaucatalyzedreactionsinwateratroomtemperature
AT handasachin micellarcatalysisenabledsustainableppmaucatalyzedreactionsinwateratroomtemperature
AT galloufabrice micellarcatalysisenabledsustainableppmaucatalyzedreactionsinwateratroomtemperature
AT lipshutzbruceh micellarcatalysisenabledsustainableppmaucatalyzedreactionsinwateratroomtemperature

Ejemplares similares