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The new era of nanotechnology, an alternative to change cancer treatment

In the last few years, nanostructures have gained considerable interest for the safe delivery of therapeutic agents. Several therapeutic approaches have been reported, such as molecular diagnosis, disease detection, nanoscale immunotherapy and anticancer drug delivery that could be integrated into c...

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Detalles Bibliográficos
Autores principales: Jurj, Ancuta, Braicu, Cornelia, Pop, Laura-Ancuta, Tomuleasa, Ciprian, Gherman, Claudia Diana, Berindan-Neagoe, Ioana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628667/
https://www.ncbi.nlm.nih.gov/pubmed/29033548
http://dx.doi.org/10.2147/DDDT.S142337
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author Jurj, Ancuta
Braicu, Cornelia
Pop, Laura-Ancuta
Tomuleasa, Ciprian
Gherman, Claudia Diana
Berindan-Neagoe, Ioana
author_facet Jurj, Ancuta
Braicu, Cornelia
Pop, Laura-Ancuta
Tomuleasa, Ciprian
Gherman, Claudia Diana
Berindan-Neagoe, Ioana
author_sort Jurj, Ancuta
collection PubMed
description In the last few years, nanostructures have gained considerable interest for the safe delivery of therapeutic agents. Several therapeutic approaches have been reported, such as molecular diagnosis, disease detection, nanoscale immunotherapy and anticancer drug delivery that could be integrated into clinical use. The current paper aims to highlight the background that supports the use of nanoparticles conjugated with different types of therapeutic agents, applicable in targeted therapy and cancer research, with a special emphasis on hematological malignancies. A particular key point is the functional characterization of nonviral delivery systems, such as gold nanoparticles, liposomes and dendrimers. The paper also presents relevant published data related to microRNA and RNA interference delivery using nanoparticles in cancer therapy.
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spelling pubmed-56286672017-10-13 The new era of nanotechnology, an alternative to change cancer treatment Jurj, Ancuta Braicu, Cornelia Pop, Laura-Ancuta Tomuleasa, Ciprian Gherman, Claudia Diana Berindan-Neagoe, Ioana Drug Des Devel Ther Review In the last few years, nanostructures have gained considerable interest for the safe delivery of therapeutic agents. Several therapeutic approaches have been reported, such as molecular diagnosis, disease detection, nanoscale immunotherapy and anticancer drug delivery that could be integrated into clinical use. The current paper aims to highlight the background that supports the use of nanoparticles conjugated with different types of therapeutic agents, applicable in targeted therapy and cancer research, with a special emphasis on hematological malignancies. A particular key point is the functional characterization of nonviral delivery systems, such as gold nanoparticles, liposomes and dendrimers. The paper also presents relevant published data related to microRNA and RNA interference delivery using nanoparticles in cancer therapy. Dove Medical Press 2017-09-27 /pmc/articles/PMC5628667/ /pubmed/29033548 http://dx.doi.org/10.2147/DDDT.S142337 Text en © 2017 Jurj et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Review
Jurj, Ancuta
Braicu, Cornelia
Pop, Laura-Ancuta
Tomuleasa, Ciprian
Gherman, Claudia Diana
Berindan-Neagoe, Ioana
The new era of nanotechnology, an alternative to change cancer treatment
title The new era of nanotechnology, an alternative to change cancer treatment
title_full The new era of nanotechnology, an alternative to change cancer treatment
title_fullStr The new era of nanotechnology, an alternative to change cancer treatment
title_full_unstemmed The new era of nanotechnology, an alternative to change cancer treatment
title_short The new era of nanotechnology, an alternative to change cancer treatment
title_sort new era of nanotechnology, an alternative to change cancer treatment
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628667/
https://www.ncbi.nlm.nih.gov/pubmed/29033548
http://dx.doi.org/10.2147/DDDT.S142337
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