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The new era of nanotechnology, an alternative to change cancer treatment
In the last few years, nanostructures have gained considerable interest for the safe delivery of therapeutic agents. Several therapeutic approaches have been reported, such as molecular diagnosis, disease detection, nanoscale immunotherapy and anticancer drug delivery that could be integrated into c...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628667/ https://www.ncbi.nlm.nih.gov/pubmed/29033548 http://dx.doi.org/10.2147/DDDT.S142337 |
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author | Jurj, Ancuta Braicu, Cornelia Pop, Laura-Ancuta Tomuleasa, Ciprian Gherman, Claudia Diana Berindan-Neagoe, Ioana |
author_facet | Jurj, Ancuta Braicu, Cornelia Pop, Laura-Ancuta Tomuleasa, Ciprian Gherman, Claudia Diana Berindan-Neagoe, Ioana |
author_sort | Jurj, Ancuta |
collection | PubMed |
description | In the last few years, nanostructures have gained considerable interest for the safe delivery of therapeutic agents. Several therapeutic approaches have been reported, such as molecular diagnosis, disease detection, nanoscale immunotherapy and anticancer drug delivery that could be integrated into clinical use. The current paper aims to highlight the background that supports the use of nanoparticles conjugated with different types of therapeutic agents, applicable in targeted therapy and cancer research, with a special emphasis on hematological malignancies. A particular key point is the functional characterization of nonviral delivery systems, such as gold nanoparticles, liposomes and dendrimers. The paper also presents relevant published data related to microRNA and RNA interference delivery using nanoparticles in cancer therapy. |
format | Online Article Text |
id | pubmed-5628667 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-56286672017-10-13 The new era of nanotechnology, an alternative to change cancer treatment Jurj, Ancuta Braicu, Cornelia Pop, Laura-Ancuta Tomuleasa, Ciprian Gherman, Claudia Diana Berindan-Neagoe, Ioana Drug Des Devel Ther Review In the last few years, nanostructures have gained considerable interest for the safe delivery of therapeutic agents. Several therapeutic approaches have been reported, such as molecular diagnosis, disease detection, nanoscale immunotherapy and anticancer drug delivery that could be integrated into clinical use. The current paper aims to highlight the background that supports the use of nanoparticles conjugated with different types of therapeutic agents, applicable in targeted therapy and cancer research, with a special emphasis on hematological malignancies. A particular key point is the functional characterization of nonviral delivery systems, such as gold nanoparticles, liposomes and dendrimers. The paper also presents relevant published data related to microRNA and RNA interference delivery using nanoparticles in cancer therapy. Dove Medical Press 2017-09-27 /pmc/articles/PMC5628667/ /pubmed/29033548 http://dx.doi.org/10.2147/DDDT.S142337 Text en © 2017 Jurj et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Review Jurj, Ancuta Braicu, Cornelia Pop, Laura-Ancuta Tomuleasa, Ciprian Gherman, Claudia Diana Berindan-Neagoe, Ioana The new era of nanotechnology, an alternative to change cancer treatment |
title | The new era of nanotechnology, an alternative to change cancer treatment |
title_full | The new era of nanotechnology, an alternative to change cancer treatment |
title_fullStr | The new era of nanotechnology, an alternative to change cancer treatment |
title_full_unstemmed | The new era of nanotechnology, an alternative to change cancer treatment |
title_short | The new era of nanotechnology, an alternative to change cancer treatment |
title_sort | new era of nanotechnology, an alternative to change cancer treatment |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628667/ https://www.ncbi.nlm.nih.gov/pubmed/29033548 http://dx.doi.org/10.2147/DDDT.S142337 |
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