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Genetic epidemiology and Mendelian randomization for informing disease therapeutics: Conceptual and methodological challenges
The past decade has been proclaimed as a hugely successful era of gene discovery through the high yields of many genome-wide association studies (GWAS). However, much of the perceived benefit of such discoveries lies in the promise that the identification of genes that influence disease would direct...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628782/ https://www.ncbi.nlm.nih.gov/pubmed/28981501 http://dx.doi.org/10.1371/journal.pgen.1006944 |