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A recombinant O-polysaccharide-protein conjugate approach to develop highly specific monoclonal antibodies to Shiga toxin-producing Escherichia coli O157 and O145 serogroups
Shiga toxin-producing Escherichia coli (STEC) is the major etiologic agent of hemolytic-uremic syndrome (HUS). The high rate of HUS emphasizes the urgency for the implementation of primary prevention strategies to reduce its public health impact. Argentina shows the highest rate of HUS worldwide, be...
Autores principales: | Castillo, Daniela S., Rey Serantes, Diego A., Melli, Luciano J., Ciocchini, Andrés E., Ugalde, Juan E., Comerci, Diego J., Cassola, Alejandro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628784/ https://www.ncbi.nlm.nih.gov/pubmed/28981517 http://dx.doi.org/10.1371/journal.pone.0182452 |
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