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Differential temperature sensitivity of synaptic and firing processes in a neural mass model of epileptic discharges explains heterogeneous response of experimental epilepsy to focal brain cooling
Experiments with drug-induced epilepsy in rat brains and epileptic human brain region reveal that focal cooling can suppress epileptic discharges without affecting the brain’s normal neurological function. Findings suggest a viable treatment for intractable epilepsy cases via an implantable cooling...
Autores principales: | Soriano, Jaymar, Kubo, Takatomi, Inoue, Takao, Kida, Hiroyuki, Yamakawa, Toshitaka, Suzuki, Michiyasu, Ikeda, Kazushi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628798/ https://www.ncbi.nlm.nih.gov/pubmed/28981509 http://dx.doi.org/10.1371/journal.pcbi.1005736 |
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