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Differential temperature sensitivity of synaptic and firing processes in a neural mass model of epileptic discharges explains heterogeneous response of experimental epilepsy to focal brain cooling

Experiments with drug-induced epilepsy in rat brains and epileptic human brain region reveal that focal cooling can suppress epileptic discharges without affecting the brain’s normal neurological function. Findings suggest a viable treatment for intractable epilepsy cases via an implantable cooling...

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Detalles Bibliográficos
Autores principales: Soriano, Jaymar, Kubo, Takatomi, Inoue, Takao, Kida, Hiroyuki, Yamakawa, Toshitaka, Suzuki, Michiyasu, Ikeda, Kazushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628798/
https://www.ncbi.nlm.nih.gov/pubmed/28981509
http://dx.doi.org/10.1371/journal.pcbi.1005736

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