Enhancing monellin production by Pichia pastoris at low cell induction concentration via effectively regulating methanol metabolism patterns and energy utilization efficiency

In heterologous protein productions by P. pastoris, methanol induction is generally initiated when cell concentration reaches very high density. The alternative strategy by initiating methanol induction at lower cells concentration was also reported to be effective in easing DO control, reducing tox...

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Detalles Bibliográficos
Autores principales: Jia, Luqiang, Tu, Tingyong, Huai, Qiangqiang, Sun, Jiaowen, Chen, Shanshan, Li, Xin, Shi, Zhongping, Ding, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628809/
https://www.ncbi.nlm.nih.gov/pubmed/28981536
http://dx.doi.org/10.1371/journal.pone.0184602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628809/
https://www.ncbi.nlm.nih.gov/pubmed/28981536
http://dx.doi.org/10.1371/journal.pone.0184602

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