The tyrosine kinase inhibitor imatinib mesylate suppresses uric acid crystal-induced acute gouty arthritis in mice

Gouty arthritis is caused by the deposition of monosodium urate (MSU) crystals in joints. Despite many treatment options for gout, there is a substantial need for alternative treatments for patients unresponsive to current therapies. Tyrosine kinase inhibitors have demonstrated therapeutic benefit i...

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Detalles Bibliográficos
Autores principales: Reber, Laurent L., Starkl, Philipp, Balbino, Bianca, Sibilano, Riccardo, Gaudenzio, Nicolas, Rogalla, Stephan, Sensarn, Steven, Kang, Dongmin, Raghu, Harini, Sokolove, Jeremy, Robinson, William H., Contag, Christopher H., Tsai, Mindy, Galli, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628843/
https://www.ncbi.nlm.nih.gov/pubmed/28982129
http://dx.doi.org/10.1371/journal.pone.0185704

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