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Microfluidic Transduction Harnesses Mass Transport Principles to Enhance Gene Transfer Efficiency

Ex vivo gene therapy using lentiviral vectors (LVs) is a proven approach to treat and potentially cure many hematologic disorders and malignancies but remains stymied by cumbersome, cost-prohibitive, and scale-limited production processes that cannot meet the demands of current clinical protocols fo...

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Detalles Bibliográficos
Autores principales:	Tran, Reginald, Myers, David R., Denning, Gabriela, Shields, Jordan E., Lytle, Allison M., Alrowais, Hommood, Qiu, Yongzhi, Sakurai, Yumiko, Li, William C., Brand, Oliver, Le Doux, Joseph M., Spencer, H. Trent, Doering, Christopher B., Lam, Wilbur A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628863/ https://www.ncbi.nlm.nih.gov/pubmed/28780274 http://dx.doi.org/10.1016/j.ymthe.2017.07.002

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