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IFN-γ alters the expression of diverse immunity related genes in a cell culture model designed to represent maturing neutrophils
The cytokine interferon-γ (IFN-γ) is approved as a drug to treat chronic granulomatous disease (CGD) and osteopetrosis and is also used in hyperimmunoglobulin E syndromes. Patients with CGD have defects in proteins of the NOX2 NADPH oxidase system. This leads to reduced production of microbicidal RO...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628906/ https://www.ncbi.nlm.nih.gov/pubmed/28982143 http://dx.doi.org/10.1371/journal.pone.0185956 |