The interplay of CD150 and CD180 receptor pathways contribute to the pathobiology of chronic lymphocytic leukemia B cells by selective inhibition of Akt and MAPK signaling

Cell surface expression of CD150 and CD180 receptors in chronic lymphocytic leukemia (CLL) associates with mutational IGHV status and favourable prognosis. Here we show a direct correlation between cell surface expression and colocalization of these receptors on CLL B cells. In the absence of CD150...

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Detalles Bibliográficos
Autores principales: Gordiienko, Inna, Shlapatska, Larysa, Kholodniuk, Valeriia, Sklyarenko, Lilia, Gluzman, Daniel F., Clark, Edward A., Sidorenko, Svetlana P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628907/
https://www.ncbi.nlm.nih.gov/pubmed/28982149
http://dx.doi.org/10.1371/journal.pone.0185940

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