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Oncogenic Hras(G12V) expression plus knockdown of Cdkn2a using ecotropic lentiviral vectors induces high-grade endometrial stromal sarcoma

The uterine corpus represents the most common site for tumour development in the female genital system. Uterine neoplasms are categorised as epithelial, mesenchymal, mixed epithelial-mesenchymal or trophoblastic tumours. In this study we employed a mouse genetic approach using the MuLE lentiviral ge...

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Detalles Bibliográficos
Autores principales:	Brandt, Laura P., Albers, Joachim, Hejhal, Tomas, Catalano, Antonella, Wild, Peter J., Frew, Ian J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628932/ https://www.ncbi.nlm.nih.gov/pubmed/28982163 http://dx.doi.org/10.1371/journal.pone.0186102

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