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Rapid functional analysis of computationally complex rare human IRF6 gene variants using a novel zebrafish model
Large-scale sequencing efforts have captured a rapidly growing catalogue of genetic variations. However, the accurate establishment of gene variant pathogenicity remains a central challenge in translating personal genomics information to clinical decisions. Interferon Regulatory Factor 6 (IRF6) gene...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628943/ https://www.ncbi.nlm.nih.gov/pubmed/28945736 http://dx.doi.org/10.1371/journal.pgen.1007009 |