Assessment of sesquiterpene lactones isolated from Mikania plants species for their potential efficacy against Trypanosoma cruzi and Leishmania sp.

Four sesquiterpene lactones, mikanolide, deoxymikanolide, dihydromikanolide and scandenolide, were isolated by a bioassay-guided fractionation of Mikania variifolia and Mikania micrantha dichloromethane extracts. Mikanolide and deoxymikanolide were the major compounds in both extracts (2.2% and 0.4%...

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Detalles Bibliográficos
Autores principales: Laurella, Laura C., Cerny, Natacha, Bivona, Augusto E., Sánchez Alberti, Andrés, Giberti, Gustavo, Malchiodi, Emilio L., Martino, Virginia S., Catalan, Cesar A., Alonso, María Rosario, Cazorla, Silvia I., Sülsen, Valeria P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629014/
https://www.ncbi.nlm.nih.gov/pubmed/28945741
http://dx.doi.org/10.1371/journal.pntd.0005929

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