Crucial role for T cell-intrinsic IL-18R-MyD88 signaling in cognate immune response to intracellular parasite infection

MyD88 is the main adaptor molecule for TLR and IL-1R family members. Here, we demonstrated that T-cell intrinsic MyD88 signaling is required for proliferation, protection from apoptosis and expression of activation/memory genes during infection with the intracellular parasite Trypanosoma cruzi, as e...

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Detalles Bibliográficos
Autores principales: Oliveira, Ana-Carolina, Gomes-Neto, João Francisco, Barbosa, Carlos-Henrique Dantas, Granato, Alessandra, Reis, Bernardo S, Santos, Bruno Maia, Fucs, Rita, Canto, Fábio B, Nakaya, Helder I, Nóbrega, Alberto, Bellio, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629024/
https://www.ncbi.nlm.nih.gov/pubmed/28895840
http://dx.doi.org/10.7554/eLife.30883

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