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Head and Neck Lymphomas in HIV Patients: a Clinical Perspective

Introduction  Because of the many HIV-related malignancies, the diagnosis and treatment of lymphoma in patients infected with human immunodeficiency virus are challenging. Objective  Here, we review current knowledge of the pathogenesis, epidemiology, symptomatology, diagnosis, and treatment of head...

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Autores principales: Oishi, Natsuki, Bagán, José Vicente, Javier, Karla, Zapater, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Revinter Publicações Ltda 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629092/
https://www.ncbi.nlm.nih.gov/pubmed/29018505
http://dx.doi.org/10.1055/s-0036-1597825
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author Oishi, Natsuki
Bagán, José Vicente
Javier, Karla
Zapater, Enrique
author_facet Oishi, Natsuki
Bagán, José Vicente
Javier, Karla
Zapater, Enrique
author_sort Oishi, Natsuki
collection PubMed
description Introduction  Because of the many HIV-related malignancies, the diagnosis and treatment of lymphoma in patients infected with human immunodeficiency virus are challenging. Objective  Here, we review current knowledge of the pathogenesis, epidemiology, symptomatology, diagnosis, and treatment of head and neck lymphomas in HIV patients from a clinical perspective. Data Synthesis  Although Hodgkin's lymphoma is not an AIDS-defining neoplasm, its prevalence is ten times higher in HIV patients than in the general population. NHL is the second most common malignancy in HIV patients, after Kaposi's sarcoma. In this group of patients, NHL is characterized by rapid progression, frequent extranodal involvement, and a poor outcome. HIV-related salivary gland disease is a benign condition that shares some features with lymphomas and is considered in their differential diagnosis. Conclusion  The otolaryngologist may be the first clinician to diagnose head and neck lymphomas. The increasing survival of HIV patients implies clinical and epidemiological changes in the behavior of this disease. Early diagnosis is important to improve the prognosis and avoid the propagation of HIV infection.
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spelling pubmed-56290922017-10-10 Head and Neck Lymphomas in HIV Patients: a Clinical Perspective Oishi, Natsuki Bagán, José Vicente Javier, Karla Zapater, Enrique Int Arch Otorhinolaryngol Introduction  Because of the many HIV-related malignancies, the diagnosis and treatment of lymphoma in patients infected with human immunodeficiency virus are challenging. Objective  Here, we review current knowledge of the pathogenesis, epidemiology, symptomatology, diagnosis, and treatment of head and neck lymphomas in HIV patients from a clinical perspective. Data Synthesis  Although Hodgkin's lymphoma is not an AIDS-defining neoplasm, its prevalence is ten times higher in HIV patients than in the general population. NHL is the second most common malignancy in HIV patients, after Kaposi's sarcoma. In this group of patients, NHL is characterized by rapid progression, frequent extranodal involvement, and a poor outcome. HIV-related salivary gland disease is a benign condition that shares some features with lymphomas and is considered in their differential diagnosis. Conclusion  The otolaryngologist may be the first clinician to diagnose head and neck lymphomas. The increasing survival of HIV patients implies clinical and epidemiological changes in the behavior of this disease. Early diagnosis is important to improve the prognosis and avoid the propagation of HIV infection. Thieme Revinter Publicações Ltda 2017-10 2017-02-01 /pmc/articles/PMC5629092/ /pubmed/29018505 http://dx.doi.org/10.1055/s-0036-1597825 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Oishi, Natsuki
Bagán, José Vicente
Javier, Karla
Zapater, Enrique
Head and Neck Lymphomas in HIV Patients: a Clinical Perspective
title Head and Neck Lymphomas in HIV Patients: a Clinical Perspective
title_full Head and Neck Lymphomas in HIV Patients: a Clinical Perspective
title_fullStr Head and Neck Lymphomas in HIV Patients: a Clinical Perspective
title_full_unstemmed Head and Neck Lymphomas in HIV Patients: a Clinical Perspective
title_short Head and Neck Lymphomas in HIV Patients: a Clinical Perspective
title_sort head and neck lymphomas in hiv patients: a clinical perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629092/
https://www.ncbi.nlm.nih.gov/pubmed/29018505
http://dx.doi.org/10.1055/s-0036-1597825
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