Cystic fibrosis swine fail to secrete airway surface liquid in response to inhalation of pathogens

Cystic fibrosis is caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) channel, which can result in chronic lung disease. The sequence of events leading to lung disease is not fully understood but recent data show that the critical pathogenic event...

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Detalles Bibliográficos
Autores principales: Luan, Xiaojie, Belev, George, Tam, Julian S., Jagadeeshan, Santosh, Hassan, Noman, Gioino, Paula, Grishchenko, Nikolay, Huang, Yanyun, Carmalt, James L., Duke, Tanya, Jones, Teela, Monson, Bev, Burmester, Monique, Simovich, Tomer, Yilmaz, Orhan, Campanucci, Veronica A., Machen, Terry E., Chapman, L. Dean, Ianowski, Juan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629252/
https://www.ncbi.nlm.nih.gov/pubmed/28983075
http://dx.doi.org/10.1038/s41467-017-00835-7

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