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Quantitative Mass Spectrometry Analysis of PD-L1 Protein Expression, N-glycosylation and Expression Stoichiometry with PD-1 and PD-L2 in Human Melanoma

Quantitative assessment of key proteins that control the tumor-immune interface is one of the most formidable analytical challenges in immunotherapeutics. We developed a targeted MS platform to quantify programmed cell death-1 (PD-1), programmed cell death 1 ligand 1 (PD-L1), and programmed cell dea...

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Detalles Bibliográficos
Autores principales:	Morales-Betanzos, Carlos A., Lee, Hyoungjoo, Gonzalez Ericsson, Paula I., Balko, Justin M., Johnson, Douglas B., Zimmerman, Lisa J., Liebler, Daniel C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Biochemistry and Molecular Biology 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629259/ https://www.ncbi.nlm.nih.gov/pubmed/28546465 http://dx.doi.org/10.1074/mcp.RA117.000037

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