MIP-MAP: High-Throughput Mapping of Caenorhabditis elegans Temperature-Sensitive Mutants via Molecular Inversion Probes

Mutants remain a powerful means for dissecting gene function in model organisms such as Caenorhabditis elegans. Massively parallel sequencing has simplified the detection of variants after mutagenesis but determining precisely which change is responsible for phenotypic perturbation remains a key ste...

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Detalles Bibliográficos
Autores principales: Mok, Calvin A., Au, Vinci, Thompson, Owen A., Edgley, Mark L., Gevirtzman, Louis, Yochem, John, Lowry, Joshua, Memar, Nadin, Wallenfang, Matthew R., Rasoloson, Dominique, Bowerman, Bruce, Schnabel, Ralf, Seydoux, Geraldine, Moerman, Donald G., Waterston, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629315/
https://www.ncbi.nlm.nih.gov/pubmed/28827289
http://dx.doi.org/10.1534/genetics.117.300179

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