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Synthesis of benzannelated sultams by intramolecular Pd-catalyzed arylation of tertiary sulfonamides
A new and efficient approach to five- and six-membered benzannelated sultams by intramolecular C-arylation of tertiary 1-(methoxycarbonyl)methanesulfonamides under palladium catalysis is described. In case of the α-toluenesulfonamide derivative, an unexpected formation of a 2,3-diarylindole was obse...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629375/ https://www.ncbi.nlm.nih.gov/pubmed/29062411 http://dx.doi.org/10.3762/bjoc.13.187 |
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author | Rassadin, Valentin A Scholz, Mirko Klochkova, Anastasiia A de Meijere, Armin Sokolov, Victor V |
author_facet | Rassadin, Valentin A Scholz, Mirko Klochkova, Anastasiia A de Meijere, Armin Sokolov, Victor V |
author_sort | Rassadin, Valentin A |
collection | PubMed |
description | A new and efficient approach to five- and six-membered benzannelated sultams by intramolecular C-arylation of tertiary 1-(methoxycarbonyl)methanesulfonamides under palladium catalysis is described. In case of the α-toluenesulfonamide derivative, an unexpected formation of a 2,3-diarylindole was observed under the same conditions. |
format | Online Article Text |
id | pubmed-5629375 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Beilstein-Institut |
record_format | MEDLINE/PubMed |
spelling | pubmed-56293752017-10-23 Synthesis of benzannelated sultams by intramolecular Pd-catalyzed arylation of tertiary sulfonamides Rassadin, Valentin A Scholz, Mirko Klochkova, Anastasiia A de Meijere, Armin Sokolov, Victor V Beilstein J Org Chem Full Research Paper A new and efficient approach to five- and six-membered benzannelated sultams by intramolecular C-arylation of tertiary 1-(methoxycarbonyl)methanesulfonamides under palladium catalysis is described. In case of the α-toluenesulfonamide derivative, an unexpected formation of a 2,3-diarylindole was observed under the same conditions. Beilstein-Institut 2017-09-12 /pmc/articles/PMC5629375/ /pubmed/29062411 http://dx.doi.org/10.3762/bjoc.13.187 Text en Copyright © 2017, Rassadin et al. https://creativecommons.org/licenses/by/4.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms) |
spellingShingle | Full Research Paper Rassadin, Valentin A Scholz, Mirko Klochkova, Anastasiia A de Meijere, Armin Sokolov, Victor V Synthesis of benzannelated sultams by intramolecular Pd-catalyzed arylation of tertiary sulfonamides |
title | Synthesis of benzannelated sultams by intramolecular Pd-catalyzed arylation of tertiary sulfonamides |
title_full | Synthesis of benzannelated sultams by intramolecular Pd-catalyzed arylation of tertiary sulfonamides |
title_fullStr | Synthesis of benzannelated sultams by intramolecular Pd-catalyzed arylation of tertiary sulfonamides |
title_full_unstemmed | Synthesis of benzannelated sultams by intramolecular Pd-catalyzed arylation of tertiary sulfonamides |
title_short | Synthesis of benzannelated sultams by intramolecular Pd-catalyzed arylation of tertiary sulfonamides |
title_sort | synthesis of benzannelated sultams by intramolecular pd-catalyzed arylation of tertiary sulfonamides |
topic | Full Research Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629375/ https://www.ncbi.nlm.nih.gov/pubmed/29062411 http://dx.doi.org/10.3762/bjoc.13.187 |
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