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Intramolecular glycosylation
Carbohydrate oligomers remain challenging targets for chemists due to the requirement for elaborate protecting and leaving group manipulations, functionalization, tedious purification, and sophisticated characterization. Achieving high stereocontrol in glycosylation reactions is arguably the major h...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629421/ https://www.ncbi.nlm.nih.gov/pubmed/29062425 http://dx.doi.org/10.3762/bjoc.13.201 |
| _version_ | 1783269047763206144 |
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| author | Jia, Xiao G Demchenko, Alexei V |
| author_facet | Jia, Xiao G Demchenko, Alexei V |
| author_sort | Jia, Xiao G |
| collection | PubMed |
| description | Carbohydrate oligomers remain challenging targets for chemists due to the requirement for elaborate protecting and leaving group manipulations, functionalization, tedious purification, and sophisticated characterization. Achieving high stereocontrol in glycosylation reactions is arguably the major hurdle that chemists experience. This review article overviews methods for intramolecular glycosylation reactions wherein the facial stereoselectivity is achieved by tethering of the glycosyl donor and acceptor counterparts. |
| format | Online Article Text |
| id | pubmed-5629421 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2017 |
| publisher | Beilstein-Institut |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-56294212017-10-23 Intramolecular glycosylation Jia, Xiao G Demchenko, Alexei V Beilstein J Org Chem Review Carbohydrate oligomers remain challenging targets for chemists due to the requirement for elaborate protecting and leaving group manipulations, functionalization, tedious purification, and sophisticated characterization. Achieving high stereocontrol in glycosylation reactions is arguably the major hurdle that chemists experience. This review article overviews methods for intramolecular glycosylation reactions wherein the facial stereoselectivity is achieved by tethering of the glycosyl donor and acceptor counterparts. Beilstein-Institut 2017-09-29 /pmc/articles/PMC5629421/ /pubmed/29062425 http://dx.doi.org/10.3762/bjoc.13.201 Text en Copyright © 2017, Jia and Demchenko https://creativecommons.org/licenses/by/4.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms) |
| spellingShingle | Review Jia, Xiao G Demchenko, Alexei V Intramolecular glycosylation |
| title | Intramolecular glycosylation |
| title_full | Intramolecular glycosylation |
| title_fullStr | Intramolecular glycosylation |
| title_full_unstemmed | Intramolecular glycosylation |
| title_short | Intramolecular glycosylation |
| title_sort | intramolecular glycosylation |
| topic | Review |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629421/ https://www.ncbi.nlm.nih.gov/pubmed/29062425 http://dx.doi.org/10.3762/bjoc.13.201 |
| work_keys_str_mv | AT jiaxiaog intramolecularglycosylation AT demchenkoalexeiv intramolecularglycosylation |