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Polyfunctional response by ImmTAC (IMCgp100) redirected CD8(+) and CD4(+) T cells

The success of immune system‐based cancer therapies depends on a broad immune response engaging a range of effector cells and mechanisms. Immune mobilizing monoclonal T cell receptors (TCRs) against cancer (ImmTAC™ molecules: fusion proteins consisting of a soluble, affinity enhanced TCR and an anti...

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Detalles Bibliográficos
Autores principales:	Boudousquie, Caroline, Bossi, Giovanna, Hurst, Jacob M., Rygiel, Karolina A., Jakobsen, Bent K., Hassan, Namir J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629433/ https://www.ncbi.nlm.nih.gov/pubmed/28640942 http://dx.doi.org/10.1111/imm.12779

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