System modeling reveals the molecular mechanisms of HSC cell cycle alteration mediated by Maff and Egr3 under leukemia

BACKGROUND: Molecular mechanisms of the functional alteration of hematopoietic stem cells (HSCs) in leukemic environment attract intensive research interests. As known in previous researches, Maff and Egr3 are two important genes having opposite functions on cell cycle; however, they are both highly...

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Detalles Bibliográficos
Autores principales: Li, Rudong, Wang, Yin, Cheng, Hui, Liu, Gang, Cheng, Tao, Liu, Yunlong, Liu, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629552/
https://www.ncbi.nlm.nih.gov/pubmed/28984203
http://dx.doi.org/10.1186/s12918-017-0467-4

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