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Incorporating genomic, transcriptomic and clinical data: a prognostic and stem cell-like MYC and PRC imbalance in high-risk neuroblastoma

BACKGROUND: Previous studies suggested that cancer cells possess traits reminiscent of the biological mechanisms ascribed to normal embryonic stem cells (ESCs) regulated by MYC and Polycomb repressive complex 2 (PRC2). Several poorly differentiated adult tumors showed preferentially high expression...

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Detalles Bibliográficos
Autores principales:	Yang, Xinan Holly, Tang, Fangming, Shin, Jisu, Cunningham, John M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629556/ https://www.ncbi.nlm.nih.gov/pubmed/28984200 http://dx.doi.org/10.1186/s12918-017-0466-5

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