Distribution of PLGA-modified nanoparticles in 3D cell culture models of hypo-vascularized tumor tissue

BACKGROUND: Advanced stage cancer treatments are often invasive and painful—typically comprised of surgery, chemotherapy, and/or radiation treatment. Low transport efficiency during systemic chemotherapy may require high chemotherapeutic doses to effectively target cancerous tissue, resulting in sys...

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Detalles Bibliográficos
Autores principales: Sims, Lee B., Huss, Maya K., Frieboes, Hermann B., Steinbach-Rankins, Jill M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629750/
https://www.ncbi.nlm.nih.gov/pubmed/28982361
http://dx.doi.org/10.1186/s12951-017-0298-x

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