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T-bet(+)CD11c(+) B cells are critical for antichromatin immunoglobulin G production in the development of lupus

BACKGROUND: A hallmark of systemic lupus erythematosus is high titers of circulating autoantibodies. Recently, a novel CD11c(+) B-cell subset has been identified that is critical for the development of autoimmunity. However, the role of CD11c(+) B cells in the development of lupus is unclear. Chroni...

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Detalles Bibliográficos
Autores principales: Liu, Ya, Zhou, Shiyu, Qian, Jie, Wang, Yan, Yu, Xiang, Dai, Dai, Dai, Min, Wu, Lingling, Liao, Zhuojun, Xue, Zhixin, Wang, Jiehua, Hou, Goujun, Ma, Jianyang, Harley, John B., Tang, Yuanjia, Shen, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629756/
https://www.ncbi.nlm.nih.gov/pubmed/28982388
http://dx.doi.org/10.1186/s13075-017-1438-2