Abnormalities in perineuronal nets and behavior in mice lacking CSGalNAcT1, a key enzyme in chondroitin sulfate synthesis

Chondroitin sulfate (CS) is an important glycosaminoglycan and is mainly found in the extracellular matrix as CS proteoglycans. In the brain, CS proteoglycans are highly concentrated in perineuronal nets (PNNs), which surround synapses and modulate their functions. To investigate the importance of C...

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Detalles Bibliográficos
Autores principales: Yoshioka, Nozomu, Miyata, Shinji, Tamada, Atsushi, Watanabe, Yumi, Kawasaki, Asami, Kitagawa, Hiroshi, Takao, Keizo, Miyakawa, Tsuyoshi, Takeuchi, Kosei, Igarashi, Michihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629790/
https://www.ncbi.nlm.nih.gov/pubmed/28982363
http://dx.doi.org/10.1186/s13041-017-0328-5

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