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Supratentorial extraparenchymal schwannoma mimicking parasagittal meningioma: A rare case report
BACKGROUND: Intracranial schwannomas not related to cranial nerves are very rare. Young age, no known history of neurofibromatosis, and seizure as initial symptom have been reported to be associated with intraparenchymal schwannoma. CASE DESCRIPTION: We report a case of supratentorial parasagittal s...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629864/ https://www.ncbi.nlm.nih.gov/pubmed/29026664 http://dx.doi.org/10.4103/sni.sni_374_16 |
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author | Raswan, Uday S. Bhat, Irfan Samoon, Nuzhat Arif, Sajad H. Laharwal, Masood Chhiber, Sarbjit S. Ramzan, Altaf Umar |
author_facet | Raswan, Uday S. Bhat, Irfan Samoon, Nuzhat Arif, Sajad H. Laharwal, Masood Chhiber, Sarbjit S. Ramzan, Altaf Umar |
author_sort | Raswan, Uday S. |
collection | PubMed |
description | BACKGROUND: Intracranial schwannomas not related to cranial nerves are very rare. Young age, no known history of neurofibromatosis, and seizure as initial symptom have been reported to be associated with intraparenchymal schwannoma. CASE DESCRIPTION: We report a case of supratentorial parasagittal schwannoma in the right frontal region presenting with seizure episode in a 70-year-old man. Computed tomography and magnetic resonance imaging showed a right frontal solid, enhancing extra-axial lesion based on anterior and middle third junction of superior sagittal sinus. The preoperative diagnosis was right parasagittal meningioma, however, the microscopic examination of the mass showed the characteristic pattern of cellular Antony A pattern. Immunohistocemically, the tumor stained positive for S-100 protein but negatively for epithelial membrane antigen and glial fibrillary acidic protein. These findings are consistent with schwannoma. Cysts, calcification, and peritumoral edema are common in intracerebral schwannoma, which were not seen in our case. CONCLUSION: On the basis of clinical presentation and radiological appearances, schwannoma in unusual sites can easily be mistaken for meningiomas; immunochemistry plays an important role in differentiating them. Till date, to the best of our knowledge, this is the second reported case of schwannoma mimicking meningioma in parasagittal location. |
format | Online Article Text |
id | pubmed-5629864 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-56298642017-10-12 Supratentorial extraparenchymal schwannoma mimicking parasagittal meningioma: A rare case report Raswan, Uday S. Bhat, Irfan Samoon, Nuzhat Arif, Sajad H. Laharwal, Masood Chhiber, Sarbjit S. Ramzan, Altaf Umar Surg Neurol Int Neuro-Oncology: Case Report BACKGROUND: Intracranial schwannomas not related to cranial nerves are very rare. Young age, no known history of neurofibromatosis, and seizure as initial symptom have been reported to be associated with intraparenchymal schwannoma. CASE DESCRIPTION: We report a case of supratentorial parasagittal schwannoma in the right frontal region presenting with seizure episode in a 70-year-old man. Computed tomography and magnetic resonance imaging showed a right frontal solid, enhancing extra-axial lesion based on anterior and middle third junction of superior sagittal sinus. The preoperative diagnosis was right parasagittal meningioma, however, the microscopic examination of the mass showed the characteristic pattern of cellular Antony A pattern. Immunohistocemically, the tumor stained positive for S-100 protein but negatively for epithelial membrane antigen and glial fibrillary acidic protein. These findings are consistent with schwannoma. Cysts, calcification, and peritumoral edema are common in intracerebral schwannoma, which were not seen in our case. CONCLUSION: On the basis of clinical presentation and radiological appearances, schwannoma in unusual sites can easily be mistaken for meningiomas; immunochemistry plays an important role in differentiating them. Till date, to the best of our knowledge, this is the second reported case of schwannoma mimicking meningioma in parasagittal location. Medknow Publications & Media Pvt Ltd 2017-09-26 /pmc/articles/PMC5629864/ /pubmed/29026664 http://dx.doi.org/10.4103/sni.sni_374_16 Text en Copyright: © 2017 Surgical Neurology International http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Neuro-Oncology: Case Report Raswan, Uday S. Bhat, Irfan Samoon, Nuzhat Arif, Sajad H. Laharwal, Masood Chhiber, Sarbjit S. Ramzan, Altaf Umar Supratentorial extraparenchymal schwannoma mimicking parasagittal meningioma: A rare case report |
title | Supratentorial extraparenchymal schwannoma mimicking parasagittal meningioma: A rare case report |
title_full | Supratentorial extraparenchymal schwannoma mimicking parasagittal meningioma: A rare case report |
title_fullStr | Supratentorial extraparenchymal schwannoma mimicking parasagittal meningioma: A rare case report |
title_full_unstemmed | Supratentorial extraparenchymal schwannoma mimicking parasagittal meningioma: A rare case report |
title_short | Supratentorial extraparenchymal schwannoma mimicking parasagittal meningioma: A rare case report |
title_sort | supratentorial extraparenchymal schwannoma mimicking parasagittal meningioma: a rare case report |
topic | Neuro-Oncology: Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629864/ https://www.ncbi.nlm.nih.gov/pubmed/29026664 http://dx.doi.org/10.4103/sni.sni_374_16 |
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