Evaluation of a Sustained-Release Prednisolone Acetate Biodegradable Subconjunctival Implant in a Non-Human Primate Model

PURPOSE: We evaluate the toxicity and plasma toxicokinetic (TK) profile of a biodegradable subconjunctival microrod for sustained prednisolone acetate (PA) release over 12 weeks in a non-human primate model. METHODS: The biodegradable copolymer poly(l-lactide-co-ε-caprolactone) (PLC) and 40-wt% PA m...

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Detalles Bibliográficos
Autores principales: Liu, Yu-Chi, Ng, Anthony Herr Cheun, Ng, Xu Wen, Yan, Peng, Venkatraman, Subbu S., Mehta, Jodhbir S., Wong, Tina T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629924/
https://www.ncbi.nlm.nih.gov/pubmed/29046829
http://dx.doi.org/10.1167/tvst.6.5.9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629924/
https://www.ncbi.nlm.nih.gov/pubmed/29046829
http://dx.doi.org/10.1167/tvst.6.5.9

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