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Evaluation of a Sustained-Release Prednisolone Acetate Biodegradable Subconjunctival Implant in a Non-Human Primate Model

PURPOSE: We evaluate the toxicity and plasma toxicokinetic (TK) profile of a biodegradable subconjunctival microrod for sustained prednisolone acetate (PA) release over 12 weeks in a non-human primate model. METHODS: The biodegradable copolymer poly(l-lactide-co-ε-caprolactone) (PLC) and 40-wt% PA m...

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Detalles Bibliográficos
Autores principales:	Liu, Yu-Chi, Ng, Anthony Herr Cheun, Ng, Xu Wen, Yan, Peng, Venkatraman, Subbu S., Mehta, Jodhbir S., Wong, Tina T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629924/ https://www.ncbi.nlm.nih.gov/pubmed/29046829 http://dx.doi.org/10.1167/tvst.6.5.9

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