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Identification of senescent cell surface targetable protein DPP4
Senescent cell accumulation in aging tissues is linked to age-associated diseases and declining function, prompting efforts to eliminate them. Mass spectrometry analysis revealed that DPP4 (dipeptidyl peptidase 4) was selectively expressed on the surface of senescent, but not proliferating, human di...
Autores principales: | Kim, Kyoung Mi, Noh, Ji Heon, Bodogai, Monica, Martindale, Jennifer L., Yang, Xiaoling, Indig, Fred E., Basu, Sandip K., Ohnuma, Kei, Morimoto, Chikao, Johnson, Peter F., Biragyn, Arya, Abdelmohsen, Kotb, Gorospe, Myriam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630018/ https://www.ncbi.nlm.nih.gov/pubmed/28877934 http://dx.doi.org/10.1101/gad.302570.117 |
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