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Massive reshaping of genome–nuclear lamina interactions during oncogene-induced senescence

Cellular senescence is a mechanism that virtually irreversibly suppresses the proliferative capacity of cells in response to various stress signals. This includes the expression of activated oncogenes, which causes Oncogene-Induced Senescence (OIS). A body of evidence points to the involvement in OI...

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Detalles Bibliográficos
Autores principales:	Lenain, Christelle, de Graaf, Carolyn A., Pagie, Ludo, Visser, Nils L., de Haas, Marcel, de Vries, Sandra S., Peric-Hupkes, Daniel, van Steensel, Bas, Peeper, Daniel S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630027/ https://www.ncbi.nlm.nih.gov/pubmed/28916540 http://dx.doi.org/10.1101/gr.225763.117

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