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Redundant and incoherent regulations of multiple phenotypes suggest microRNAs’ role in stability control
Each microRNA (miRNA) represses a web of target genes and, through them, controls multiple phenotypes. The difficulties inherent in such controls cast doubt on how effective miRNAs are in driving phenotypic changes. A “simple regulation” model posits “one target–one phenotype” control under which mo...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630030/ https://www.ncbi.nlm.nih.gov/pubmed/28904014 http://dx.doi.org/10.1101/gr.222505.117 |