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RNA editing in bacteria recodes multiple proteins and regulates an evolutionarily conserved toxin-antitoxin system

Adenosine (A) to inosine (I) RNA editing is widespread in eukaryotes. In prokaryotes, however, A-to-I RNA editing was only reported to occur in tRNAs but not in protein-coding genes. By comparing DNA and RNA sequences of Escherichia coli, we show for the first time that A-to-I editing occurs also in...

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Detalles Bibliográficos
Autores principales: Bar-Yaacov, Dan, Mordret, Ernest, Towers, Ruth, Biniashvili, Tammy, Soyris, Clara, Schwartz, Schraga, Dahan, Orna, Pilpel, Yitzhak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630033/
https://www.ncbi.nlm.nih.gov/pubmed/28864459
http://dx.doi.org/10.1101/gr.222760.117